The Role of Dopaminergic Neurodegeneration in Equine Pituitary Pars Intermedia Dysfunction (Equine Cushing's Disease) (21-Nov-2003)
نویسندگان
چکیده
Equine pituitary pars intermedia dysfunction (PPID) is a well-recognized disease in aged horses and ponies, yet the etiology and pathophysiology of this condition remains poorly understood. Immunohistochemistry of formalin-fixed pituitary tissue was used to demonstrate dopaminergic neurodegeneration and oxidative stress in the pars intermedia in horses with PPID. The role of oxidative stress in the pathophysiology of this disease is a new finding. Further research is warranted to elucidate the mechanism resulting in oxidative stress in horses with PPID.
منابع مشابه
Pituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease)
Copyright ©NADIS 2017 Pituitary Pars Intermedia Dysfunction (PPID) is the correct term for the disease commonly known as Equine Cushing's Disease. The latter term is technically incorrect because it is now known that the disease is different from human Cushing's disease. It is a condition of older horses and typically develops in horses over 15 years of age although it can develop in younger an...
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